The hemodynamic changes showed no regional preference across the ONH, which was consistent with postmortem histological observations. After IOP was increased to 30 mm Hg, global blood flow was significantly reduced ( P < 0.001), but with no regional preferences despite prominent temporal RNFLT loss no significant blood flow change was observed in control eyes ( P = 0.24).īasal blood flow and autoregulation capacity in the ONH of BOA were significantly compromised, with a close correlation to structural changes.
These blood flow changes were significantly correlated with corresponding sectoral RNFLT ( P < 0.01) except the nasal ( P = 0.25). Spectral-domain optic coherence tomography was used to measure retinal nerve fiber layer thickness (RNFLT) by peripapillary circular scans.Ĭompared with control eyes, RNFLT in BOA eyes was significantly less in all sectors ( P < 0.001) except the nasal ( P = 0.25) the average global and sectoral blood flow in all quadrants was significantly lower ( P < 0.001). Basal blood flow in global and quadrantal sectors was measured with IOP set at 10 mm Hg autoregulation capacity was assessed by comparing blood flow changes before and after IOP was increased from 10 to 30 mm Hg. ONH blood flow was measured with a laser speckle flow graph device. In five animals with BOA and nine healthy animals under general anesthesia (pentobarbital), intraocular pressure (IOP) was manometrically controlled. Send us feedback about these examples.To characterize the hemodynamic features and the association with structural damage in the optic nerve head (ONH) of idiopathic bilateral optic atrophy (BOA) in rhesus macaque monkeys.
These examples are programmatically compiled from various online sources to illustrate current usage of the word 'pupil.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors.
2023 The room is lit by four fluorescent circular fixtures overhead, which reflect off the white lacquered surface of a large conference table like ring lights off a pupil. Victoria Sayo Turner, Smithsonian Magazine, 16 Aug. 2023 As far back as the 1800s, French scientists found that, after surgically attaching two rats, injecting a compound from a deadly nightshade plant into one rat could dilate the pupils of the other, the Times reports. 2023 The third graders’ enthusiasm spiked several minutes later when they were ushered to the playground where McGill, Bahati and race organizers of this weekend’s Maryland Cycling Classic gave each pupil a red bicycle and a blue or purple-and-white helmet. 2023 An individual may be overdosing if his or her breathing is slowed or stopped, and the pupils of the eyes narrow to a pinpoint. 2023 The Guardian adds that the 17 pupils are the second largest group of multiples on record to be enrolled.
2023 Most of her irises are black except for the white concentric circles near the pupil that almost make her eyes look like a never-ending maze. 2023 Police received a separate tip that the pupil was supplying other students with nicotine and vape products containing THC, the active ingredient in marijuana. Noun White, grayish-white, or yellow-color material in the pupil.
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